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Author

J. van Loosdregt

2 papers indexed here

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Open access Sep 2026

Persistent IL-18 fuels expansion of CD38+HLA-DR+CD8+ T cells in Still's disease and macrophage activation syndrome.

OBJECTIVE Still's disease (SD) is an autoinflammatory disorder characterized by remarkably high IL-18 levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is asso...

Greta Rogani, R. Erkens, A. Bodelón et al. · 0 citations

can modulate TAL1 transcriptional activity through interaction with LMO2

Initial evidence for a novel role of FOXP3 as a tumor suppressor in T-ALL through modulation of TAL1 transcriptional activity is provided through modulation of TAL1 transcriptional activity.

V. Fleskens, M. Mokry, A. M. van der Leun et al. · 0 citations

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