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J. Tye-Din

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Open access Sep 2026

Single-cell multi-omics maps clonal IEL expansion and epithelial remodelling in refractory coeliac disease

Background Refractory coeliac disease type 1 (RCD1) lacks defining molecular markers, and the immune and epithelial mechanisms sustaining intestinal injury remain poorly understood. Objective To define the clonal immune and epithelial states that distinguish RCD1 from active coeliac disease (ACD) and determine their sp...

Michael Li, Arman Safavi, J. Samir et al. · 0 citations
Review Open access Jul 2026

Next-generation immunoassays for autoantibody detection in celiac disease: emerging technologies and diagnostic advances.

The future role of Aab in the diagnostic algorithm of CeD is outlined and the next-generation techniques that could replace the conventional testing methods are highlighted to replace the conventional ELISA and RBA techniques in the near future.

A. Lomash, Alexander Lind, K. Kurppa et al. · 0 citations

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