Open access
Sep 2026
Brain organoid computing for robotic decision-making
Hongwei Cai, Chunhui Tian, Yang Yang et al.
· bioRxiv · 0 citations
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Open access
Sep 2026
Engineering human myelin microphysiological systems for testing patient treatment response in multiple sclerosis
Chunhui Tian, Zheng Ao, Hongwei Cai et al.
· bioRxiv · 0 citations
Open access
Jan 2026
Multiomic Investigation of Shared Genetic Pathways in Paediatric Congenital Heart Disease and Neurodevelopmental Disorders
DNA methylation analysis revealed epigenetic differences between CHD and NDD patients, with CHD patients showing elevated biological age acceleration and the findings highlight the diagnostic and mechanistic value of integrative multiomic profiling in paediatric developmental disease cohorts.
Jamie-Lee M. Thompson, Yun-Kai Gao, Eri Iwasawa et al.
· Human Mutation · 0 citations
Open access
Jul 2026
The m6A-mediated epi-transcriptomic dysregulation drives synaptic dysfunction in fragile X syndrome.
It is demonstrated that FMRP deficiency drives the aberrant translational upregulation of core m6A writers, a causal relationship definitively validated using CGG-corrected isogenic control lines and suggest a promising avenue for m6A-targeted therapies.
Lu Lu, Avijite Kumer Sarkar, Lan Dao et al.
· Molecular Psychiatry · 0 citations