Endophytic fungi are significant sources of structurally diverse natural products with promising pharmacological and biological applications. In this study, endophytic fungi isolated from Ocotea diospyrifolia leaves were investigated as potential producers of anti-inflammatory natural products using an integrated workf...
Giovanni S. Oliveira, M. Marques, Ana L. U. Nascimento et al.· Molecules· 0 citations
Novel compounds from natural sources that can inhibit and eradicate Candida albicans biofilms were investigated. Four compounds (26.7%) inhibited 50% or more biofilm formation at a single dose out of fifteen compounds evaluated. Among them, three terpenoid derivatives (2, 4 and 6) did not show antifungal activity at th...
Carolina Do Rosário Esteves Guimarães, H. F. de Freitas, T. D. de Souza et al.· Natural Product Research· 0 citations
Natural products represent an important source of candidates for breast cancer therapy. Here, we investigated the antitumor activity of (E)-4-(1-epoxy-7,8-propen)phenylbenzoate (CV2), a phenylpropanoid isolated from Croton velutinus roots, in MCF-7 breast cancer cells and evaluated its toxicity profile in nontumor ce...
R. A. de Abrantes, S. Duarte, R. Ferreira et al.· ACS Omega· 0 citations
Annona amazonica R. E. Fries (Annonaceae) is a tropical species native to Central and South America whose phytochemical profile remains poorly investigated. In the present study, the bark of A. amazonica was subjected to phytochemical investigation using conventional chromatographic techniques, leading to the isolation...
J. F. Auzier, Thayline Rayany Batista Menezes, Maria Lúcia Belém Pinheiro et al.· Molecules· 0 citations
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