Preeclampsia is a multifactorial hypertensive disorder of pregnancy with major clinical consequences. Adipokines-bioactive peptides secreted by adipose tissue-may contribute to its pathogenesis through mechanisms involving inflammation, angiogenesis, and endothelial dysfunction. This review summarizes findings from var...
M. Motaqi, Mahsa Mehrabadi, Zainb A. Talib et al.· Cytokine· 0 citations
Background: Depressive symptoms, anxiety symptoms, and low subjective well-being are highly prevalent among older adults, but they are typically assessed separately, and their co-occurrence remains insufficiently explored, particularly in Central Asia. Objectives: This study aimed to assess the prevalence and co-occurr...
Mariya Bekbolatova, A. Baibussinova, Z. Khismetova et al.· International Journal of Env...· 0 citations
Mutation-based liquid biopsy supports diagnosis and disease monitoring in hematologic malignancies, but interpretation of plasma variants may be complicated by clonal hematopoiesis, treatment-related changes, and nonmalignant blood-cell turnover. This structured narrative review evaluates whether cell-free DNA (cfDNA)...
Amr A. El-Sehrawy, Sarmad S. Abdullah, Guzalya Mamedova et al.· Translational Oncology· 0 citations
Sepsis is a critical medical state considered a life-threatening response to infection, leading to extensive inflammation and potential organ dysfunction. This systematic review focuses on the therapeutic impact of baicalin on sepsis complications.
METHODS
This systematic review followed PRISMA guidelines and was reg...
Usamah Sayed, Naji Musa Ali, S. Jyothi et al.· Natural Product Research· 0 citations
FOXM1, a forkhead-box transcription factor, is consistently overexpressed in breast cancer, particularly in the basal-like and triple-negative subtypes, in which high expression predicts poor survival. We propose, as a falsifiable hypothesis rather than an established mechanism, that FOXM1 may function as a dosage-inte...
G. Oriquat, Hani Moslem Ahmed, J. Rizaev et al.· Frontiers in Oncology· 0 citations
Cancer remains a leading cause of morbidity and mortality worldwide, demanding innovative strategies for diagnosis, therapy, and immune modulation. Advances in nanomedicine have positioned MXene quantum dots (MQDs) as promising multifunctional platforms for cancer theranostics due to their tunable physicochemical pro...
T. AlRamadneh, J. Rizaev, Jakhongir Norqulov et al.· Surface and Interface Analys...· 0 citations
Congenital hydronephrosis caused by ureteropelvic junction obstruction (UPJO) remains one of the main causes of chronic kidney disease in childhood. Laparoscopic pyeloplasty has become the standard of treatment; however, in young children its performance is associated with technical difficulties. In addition, tradition...
I. Akhmedov, S. P. Yatsyk, J. Rizaev et al.· PEDIATRIA Journal named afte...· 0 citations
The development of tuberculosis (TB) is dictated by a complicated interplay between antimicrobial defense and host‐mediated immunopathology. Neutrophils are known to exhibit striking functional plasticity with phenotypes associated with both bacterial containment and tissue damage. However, the mechanisms that connect...
K. Hamdan, J. Rizaev, Dhara N. Patel et al.· Cell Biology International· 0 citations
The transcriptional coactivators p300 and CREB-binding protein (CBP) integrate chromatin remodeling, enhancer activity, lysine acetylation, immune signaling, and tumor-suppressor control, making them recurrent targets of viral proteins. This narrative review examines p300/CBP at the virus-cancer interface, prioritizing...
A. Atoom, J. Rizaev, D. Polatova et al.· Cancer Treatment and Researc...· 0 citations
Oncolytic virotherapy has evolved from a tumor-selective cytolytic strategy into a programmable immunotherapeutic platform that reshapes the tumor microenvironment (TME). Oncolytic viruses (OVs) selectively infect malignant cells, induce immunogenic cell death, release tumor antigens, and activate innate and adaptive i...
A. Atoom, J. Rizaev, D. Polatova et al.· Cancer Treatment and Researc...· 0 citations
The regulatory mechanisms linking ferroptosis and the tumor immune microenvironment are highlighted, a critical discussion of recent developments in bionanomaterial‐based therapeutic platforms is provided, and the challenges and prospects for clinical application of these platforms for immunotherapy are outlined.
Usamah Sayed, J. Rizaev, R. Turaev et al.· Journal of Cellular Biochemi...· 0 citations
This review integrates current knowledge of circRNA biogenesis and molecular function, surveys cancer-type-specific circRNA expression signatures, and evaluates evidence for their utility in MRD monitoring across hematologic and solid malignancies, and proposes multilayered diagnostic frameworks combining circRNA profi...
T. Alramadneh, Hussein Salim Abed, Sarah Qutayba Badraldin Qutayba Badraldin et al.· Journal of Investigative Med...· 0 citations
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