J. Resident

TUMOR MICROENVIRONMENT: EMERGING INSIGHTS INTO CANCER PROGRESSION AND THERAPEUTIC TARGETS - A NARRATIVE REVIEW

The tumor microenvironment (TME) is increasingly recognized as a dynamic and biologically active ecosystem that profoundly influences cancer initiation, progression, metastasis, immune escape, and therapeutic resistance. Rather than functioning as an isolated mass of malignant cells, a tumor consists of complex interac...

Musculoskeletal Comorbidities and Physical Activity Patterns in Adults Aged 50 Years and Above with Acute Low Back Pain in Rural Goa

COMPARISON OF LOW DOSE SUGAMMADEX WITH NEOSTIGMINE PLUS GLYCOPYRROLATE VERSUS NEOSTIGMINE PLUS GLYCOPYRROLATE FOR EXTUBATION

Background: Residual neuromuscular blockade remains a significant cause of delayed recovery and postoperative respiratory complications following general anaesthesia. Neostigmine with glycopyrrolate is the conventional reversal regimen but may be associated with incomplete recovery. Sugammadex provides rapid and predic...

TOTAL INTRAVENOUS ANAESTHESIA (TIVA): PHARMACOLOGY AND CLINICAL APPLICATIONS

Total Intravenous Anaesthesia (TIVA) has been a major technique in anaesthesia and has been adopted since the use of hypnotic and analgesic intravenous drugs for stable anaesthesia without using inhalational drugs. Rapid onset, predictable recovery profile, antiemetic effect, low environmental contamination and haemody...