Cancer cachexia is a multifactorial and progressive syndrome characterized by the not fully reversible loss of skeletal muscle and adipose tissue, which significantly impairs treatment tolerance, quality of life, and patient survival. Despite its high clinical burden, cachexia remains underdiagnosed and undertreated, l...
Rita Lima-Sousa, Aike Sijtsma, Lucília Pereira da Silva et al.· Seminars in Cancer Biology· 0 citations
This substudy aimed to explore the effects of YAQ001 on the gut microbiome and their exploratory association with biomarkers of gut permeability and systemic inflammation.
Jin-Xia Liu, F. Garcia-Guevara, J. Macnaughtan et al.· Liver international (Print)· 0 citations
A modular human three-dimensional bioengineered liver–muscle platform is developed to dissect causal liver–muscle crosstalk and provides a testbed for perturbations and interventions targeting liver-driven muscle wasting.
A. Cortés-Reséndiz, J. Fernández-Costa, M. Sabater-Arcís et al.· Disease Models & Mechanisms· 1 citation
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