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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

J. Perilla

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Open access Sep 2026

MxB N-Terminus Adopts a Stable α-Helix to Engage the HIV-1 Capsid Trimer Interface

The HIV-1 capsid, composed of capsid (CA) proteins arranged into a conical surface lattice, serves as a critical platform for host–pathogen interactions. Many host cofactors regulate HIV-1 infection by selectively recognizing the higher-order CA lattice rather than individual monomers or capsomers. Among these, Myxovir...

Ya-Nan Zhu, J. Rey, Juan Shen et al. · 0 citations
Open access Sep 2026

Inositol Hexakisphosphate Promotes Open Pore State in HIV Capsid Protein Lattice by Reconfiguring Subunit Contacts

IP6 is established as a proviral regulator that couples nanoscale pore dynamics, intersubunit contact reconfiguration, and mechanical resilience of the HIV-1 capsid, providing a unified mechanistic framework for its role in viral replication.

Y. Knelissen, Judith Escrig, Amanda C. Macke et al. · 0 citations
Open access Aug 2026

Stoichiometric Binding of Cyclophilin-A to The HIV-1 Capsid Modulates Its Mechanoelastic Properties.

Atomic force microscopy nanoindentation simulations of CypA-decorated capsids reveal that CypA acts as a stoichiometric regulator of capsid mechanical response, highlighting how surface ligand binding programs the mechanical response of protein nanocapsules, offering principles for stimuli-responsive biomolecular mater...

J. Rey, Alexander J. Bryer, J. Perilla · 0 citations

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