Acid-degradable hollow calcium-manganese nanocarriers integrate calcium stress, redox catalysis, and antitumor immunity for lung cancer therapy.
Non-small cell lung cancer (NSCLC) remains a major cause of cancer-related mortality, while acquired resistance to EGFR-targeted therapy and an immunosuppressive tumor microenvironment continue to limit therapeutic efficacy. Here, we developed a tumor cell membrane-coated, acid-degradable hollow calcium-manganese nanop...