Pathway-Dependent Formation of Compact Polypeptide-Based Single-Chain Nanoparticles
Single-chain nanoparticles (SCNPs) are synthetic macromolecules that undergo intramolecular collapse to form protein-sized structures (5–20 nm), making them attractive as protein mimics whose peptide backbone is expected to confer susceptibility to enzymatic and hydrolytic degradation. While most reported SCNPs rely...