Detection of Diabetes Autoantibodies (ZnT8A and GADA) by Bridge Fluorophore-Linked Immunosorbent Assay Using Baculovirus Expressed ZnT8/GAD65 Chimera
Background: Type 1 Diabetes Mellitus (T1DM) is preceded by a prolonged asymptomatic autoimmune phase during which islet autoantibodies represent the earliest detectable biomarkers of disease. Although Radioligand Binding Assays (RBAs) remain the reference method for autoantibody detection, their use is limited by the r...