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Jean-François Mangin

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#machine learning Preprint Sep 2026

Geometric-to-Semantic Spherical Transfer Learning for Cortical Sulci Labeling

A Geometric-to-Semantic Spherical Transfer Learning framework that outperforms fully supervised baselines trained from scratch on variable and tertiary sulci, confirming that learning the cortex shape is highly beneficial for identifying its rarest parts.

Saeb Tounsi, J. Chavas, Pietro Gori et al. · 0 citations

Representation learning of human cortical folding to reveal long lasting neurodevelopmental signatures.

Champollion, a self-supervised learning framework that learns interpretable local representations of cortical folding from structural MRI, is introduced, establishing cortical folding as a rich and largely untapped source of neurodevelopmental information.

Julien Laval, R. Guiavarch, Antoine Dufournet et al. · 1 citation
Open access Jul 2026

A Comparative Study of Aging and Cortical Folding in Chimpanzees and Olive Baboons

It is found that variation in primate social systems and/or reproductive aging may influence sex and species differences in brain aging, and within the baboons but not the chimpanzees, significant sex differences were found in age‐related differences in cortical folding.

William D Hopkins, Angela M. Achorn, M. M. Mulholland et al. · 0 citations
#protein folding Open access Aug 2026

Clinically Relevant Biomarkers of Alzheimer’s Disease Are Associated with Age and Cortical Atrophy in Chimpanzees (Pan troglodytes)

This work believes this is the first evidence demonstrating an association between these clinically relevant biomarkers of Alzheimer’s disease and phenotypes of brain aging in nonhuman primates, underscoring their importance as models of aging and neurodegenerative disease.

M. Mulholland, Elizabeth R. Magden, Angela M. Achorn et al. · 0 citations

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