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Open access Sep 2026

Electrochemical DNA hairpin sensors for differentiating small molecule intercalation from minor groove binding

Small molecule double-stranded DNA intercalators have significant potential for therapeutic applications. However, screening for and confirming a drug candidate's intercalative behavior remains labor-intensive and costly. To address this, we investigated the sequence and biophysical parameters that affect the performan...

Kiara Thompson, K. Barnes, Saron P. Yoseph et al. · 0 citations

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