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Review Open access Oct 2026

Uncovering the Role of Small and Intermediate-Length Non-Coding RNAs in Glioma Pathogenesis and Prognosis

Gliomas are the most prevalent and aggressive primary tumors of the central nervous system (CNS), with glioblastoma demonstrating particularly poor survival rates despite multimodal treatment approaches. The extensive molecular heterogeneity and resistance to conventional therapies highlight the urgent need for novel b...

J. Machhi, Priya U. Kumthekar, Stella Hartmann · 0 citations
Open access Aug 2026

KRAS and TP53 Circulating Tumor DNA are Prognostic in Localized Pancreatic Cancer.

BACKGROUND Pancreatic ductal adenocarcinoma (PDAC) carries high mortality despite neoadjuvant chemotherapy (NAC) and surgical resection, creating an urgent need for prognostic biomarkers to guide treatment. We aimed to determine whether circulating tumor DNA (ctDNA) detected by next-generation sequencing (NGS) predicts...

Krishay Sridalla, Dominic J. Vitello, Madison Cox et al. · 0 citations

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