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J. Ludvigsson

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Open access Oct 2026

Platelet P2Y12 inhibitor use and risk of colorectal cancer incidence and colorectal cancer-related mortality: a Swedish registry-based cohort study

Low-dose aspirin use is associated with reduced CRC incidence and CRC-related mortality. A similar association with P2Y12 inhibitor use remains uncertain. We investigated whether the use of P2Y12 inhibitors was associated with CRC incidence and CRC-related mortality among individuals diagnosed with atherosclerotic card...

Michael Fuchs, Jane Ha, Jane Yan et al. · 0 citations
Open access Sep 2026

Human papillomavirus infection and risk of cardiovascular disease: A population-based matched cohort study with sibling analysis

Background The role of human papillomavirus (HPV) in cardiovascular disease (CVD) remains unclear. We aimed to investigate the associations of HPV infection with incident CVD and CVD-related mortality. Methods and findings In this population-based matched cohort study based on Swedish national registers, we identified...

Yun-Yang Deng, M. Clements, Chaonan Shen et al. · 0 citations
Sep 2026

Integrated metabolomic and genetic profiling implicate loss of docosahexaenoic acid in the link between ultra-processed foods and Crohn's disease.

Lower circulating DHA may represent one metabolic pathway linking UPF intake to increased CD risk, apart from additive harm to metabolic depletion, which highlights potential targets for precision nutrition in CD prevention in future trials.

Si-Dan Wang, Lin-Tao Dan, Xi-Xian Ruan et al. · 0 citations
Open access Sep 2026

Impact of Family History on Colorectal Cancer Risk in Inflammatory Bowel Disease and in Matched General Population Comparators.

Family history of CRC increased CRC incidence similarly in IBD and matched comparators, with the greatest increase in individuals with multiple affected relatives, raising the question if surveillance strategies should instead prioritize patients with multiple affected relatives.

Å. H. Everhov, Kári Kristjánsson, J. Ludvigsson et al. · 0 citations

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