BACKGROUND
Hypertrophic cardiomyopathy (HCM) is a heritable trait with marked variability in expression and outcomes. Our aims were to discover new genetic loci associated with HCM and to test the effect of a new polygenic risk score (PRS) on incidence, phenotype and outcomes stratified by genotype status.
METHODS
A...
Luis R. Lopes, Nay Aung, S. van Duijvenboden et al.· Journal of Medical Genetics· 0 citations
BACKGROUND
Excessive trabeculation of the left ventricle (ETLV) is a heterogeneous and controversial phenotype that overlaps with both physiological remodeling and cardiomyopathy.
OBJECTIVES
This study sought to develop and validate a cardiac magnetic resonance (CMR)-based model to predict major adverse cardiovascula...
Guillem Casas, E. Ródenas-Alesina, Javier Limeres et al.· JACC Cardiovascular Imaging· 0 citations
These findings support systematic GT in HTx recipients with CM, including those with prior environmental triggers or second-hit etiologies, and regardless of time from transplantation.
C. Moliner-Abós, D. C. Cabrera Argana, David Belmar Cliville et al.· JACC: Advances· 2 citations
These findings support MVA multiparametric prediction over the traditional left ventricular ejection fraction ≤35% threshold and allow clinically meaningful arrhythmic risk classification in patients with nonischemic dilated cardiomyopathy.
Noemí Ramos-López, N. Mora-Ayestarán, Juan Pablo Ochoa et al.· Circulation· 0 citations
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