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J. Kustermann

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Open access Aug 2026

Frailty in Adults With Down Syndrome: Cognitive, Functional and Biomarker Associations.

BACKGROUND Down syndrome (DS) entails widespread age-related functional decline affecting multiple organ systems, including genetically determined early-onset Alzheimer disease (DSAD), resulting in an increased vulnerability to frailty early in life. We investigated the relationship between frailty, cognition and intel...

Georg S. Nuebling, Lena Marth, K. Sandkühler et al. · 0 citations

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