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J. Killestein

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Open access Oct 2026

Training effects in oculography in multiple sclerosis patients: a one-year longitudinal study.

PURPOSE Longitudinal quantitative data on eye movement abnormalities in people with multiple sclerosis (PwMS) are scarce, and the impact of repeated oculomotor testing on these measures is unknown. We aimed to use infrared oculography to characterise one-year changes in oculomotor metrics in PwMS and to determine wheth...

S. Hof, P. Molenaar, Ka-Hoo Lam et al. · 0 citations
Open access Sep 2026

Comorbidities and infectious episodes in multiple sclerosis patients within general practices in the Netherlands.

BACKGROUND People with multiple sclerosis (PwMS) are at heightened risk of comorbidities and infections, due to the disease's debilitating nature and side effects of disease-modifying therapies (DMT). METHODS This retrospective case-control study was conducted the Dutch Nivel Primary Care Database from the year 2019,...

Cynthia M. C. Lemmens, Joost W. Vanhommerig, Bart J. Knottnerus et al. · 0 citations
Jul 2026

Anti-CD20 B cell depletion is associated with elevated mucosal-originating circulating regulatory IgA B cells in multiple sclerosis.

It is found that anti-CD20 B cell depletion was associated with increased frequencies of regulatory mucosal-derived IgA-producing B cells in the periphery and CSF, together with increased B cell receptor clonal overlap between mucosal and systemic compartments, indicating enhanced trafficking of IgA B cells from gut mu...

T. Neziraj, Elisabeth Pössnecker, Angela A. Wang et al. · 0 citations
Open access Jul 2026

The value of brain age as a transdiagnostic biomarker of neurodegeneration

It is demonstrated that brain-PAD is a clinically meaningful, transdiagnostic biomarker of neurodegeneration that complements conventional volumetric measures like the BPF.

Lonneke Bos, D. V. van Nederpelt, J. Cole et al. · 0 citations

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