PURPOSE
Longitudinal quantitative data on eye movement abnormalities in people with multiple sclerosis (PwMS) are scarce, and the impact of repeated oculomotor testing on these measures is unknown. We aimed to use infrared oculography to characterise one-year changes in oculomotor metrics in PwMS and to determine wheth...
S. Hof, P. Molenaar, Ka-Hoo Lam et al.· Graefe's archive for clinica...· 0 citations
BACKGROUND
People with multiple sclerosis (PwMS) are at heightened risk of comorbidities and infections, due to the disease's debilitating nature and side effects of disease-modifying therapies (DMT).
METHODS
This retrospective case-control study was conducted the Dutch Nivel Primary Care Database from the year 2019,...
Cynthia M. C. Lemmens, Joost W. Vanhommerig, Bart J. Knottnerus et al.· Multiple Sclerosis and Relat...· 0 citations
It is found that anti-CD20 B cell depletion was associated with increased frequencies of regulatory mucosal-derived IgA-producing B cells in the periphery and CSF, together with increased B cell receptor clonal overlap between mucosal and systemic compartments, indicating enhanced trafficking of IgA B cells from gut mu...
T. Neziraj, Elisabeth Pössnecker, Angela A. Wang et al.· Science Translational Medici...· 0 citations
It is demonstrated that brain-PAD is a clinically meaningful, transdiagnostic biomarker of neurodegeneration that complements conventional volumetric measures like the BPF.
Lonneke Bos, D. V. van Nederpelt, J. Cole et al.· medRxiv· 0 citations
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