Author

J. Jeong

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Open access Oct 2026

Sequence-based variant-effect predictions reveal trait-specific regulatory-layer profiles of complex-trait heritability

Differences across traits in the heritability information captured by predicted regulatory layers are identified and testable hypotheses for investigating the regulatory basis of complex traits are offered.

B. Choi, J. Jeong · medRxiv · 0 citations

Open access Oct 2026

Expression predictions inform molecular interpretation of Alzheimer's disease risk loci

Sequence models predict the molecular effects of genetic variation, yet their contribution to interpreting Alzheimer's disease (AD) association signals remains uncertain. Here we analysed AlphaGenome Atlas predictions for 111,446 common variants across 75 regions from a European-ancestry genome-wide association study (...

C. B. Hyug, J. Jeong · medRxiv · 0 citations