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Author

J. Jee

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Open access Sep 2026

Systemic iron sequestration restricts the intratumoral CD8+ T cell landscape in pancreas cancer

Systemic iron sequestration occurs frequently in cancer due to inflammation-driven expression of the iron-regulatory hormone hepcidin. The impact of systemic iron availability on tumoral immunity is unclear. Here, we show that elevated serum hepcidin is associated with reduced survival and decreased intratumoral CD8+ T...

J. Schoenfeld, Jahi J. Noel, Christopher S. McGinnis et al. · 0 citations
Aug 2026

The pan-tumor landscape, allelic status, and genomic complexity of SMARCA4 alterations.

SMARCA4 alteration class and allelic status define biologically and clinically distinct subsets of tumors and support incorporating allelic status and functional mutation class into patient selection strategies for emerging BRM-targeted therapies.

M. Repetto, M. Gormally, Jason Chang et al. · 0 citations

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