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J. Herrmann

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Open access Oct 2026

Cysteine-Based Amino Acid Mimetics as First-in-Class Antitubercular Agents: Discovery, SAR, and Identification of a Lead Compound with Intracellular Activity

Tuberculosis (TB), caused byMycobacterium tuberculosis (Mtb), remains a leading global infectious disease killer, and the emergence of drug-resistant strains underscores the urgent need for new antitubercular agents with novel mechanisms of action. Herein, we report the discovery of cysteine-based amino acid mimetics...

Tomayo I. Berida, Destinee L. Manning, Samuel R. McKee et al. · 0 citations

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