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Open access Sep 2026

Anti-Müllerian hormone in relation to adiposity and metabolic indices in polyendocrine metabolic ovarian syndrome

Anti-Müllerian hormone (AMH) is widely used as a marker of ovarian reserve and is also incorporated into the diagnostic assessment of polyendocrine metabolic ovarian syndrome (PMOS). Although PMOS is strongly associated with metabolic dysfunction and abnormal adipose tissue distribution, the relationship between AM...

Karolina Kowalczyk, Dominika Gałczyńska, J. Herman et al. · 0 citations
Review Open access Sep 2026

Causal relationship between liver fat reduction and clinical outcomes in human genetic studies and randomized clinical trials of metabolic-dysfunction associated steatohepatitis

Reliance on invasive liver biopsy endpoints is a major limiting factor in new therapeutic development for metabolic dysfunction-associated steatohepatitis (MASH). While liver fat accumulation is considered a driver of early disease, liver fat reduction is not recognized as a surrogate endpoint by health authorities. He...

N. Verweij, G. Hindy, Q. Nguyen et al. · 0 citations

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