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J. Henes

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Review Open access Sep 2026

Methotrexate Versus Mycophenolate Mofetil as First-Line Therapy in Systemic Sclerosis: Evidence from Clinical Trials and Real-World Studies—A Narrative Review

Systemic sclerosis (SSc) is a heterogeneous autoimmune connective tissue disease characterized by immune activation, vasculopathy and progressive fibrosis of the skin and internal organs. Immunosuppressive treatment is commonly used in early inflammatory disease and in SSc-associated interstitial lung disease (SSc-ILD)...

J. Henes, Luisa Schneider, Johannes Olschner et al. · 0 citations

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