Microglial dynamics associate with the spatial pattern of tau deposition in early Alzheimer’s disease
Neuroinflammation is implicated in Alzheimer’s disease (AD) pathogenesis, yet how changes in TSPO PET signal are associated with tau deposition, and how brain network architecture shapes this relationship remain poorly understood. We conducted a prospective, multimodal neuroimaging study in 56 participants: 35 amyloid-...