Author

J. Goodall

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Review Open access Oct 2026

Virulence Mechanisms of Streptococcus pneumoniae During Co-Infection

Streptococcus pneumoniae (pneumococcus) represents a key clinical challenge, being a major global cause of morbidity and mortality. Typically existing as a nasopharyngeal commensal, pneumococcus undergoes significant metabolic changes during its switch to a virulent pathogen, when it can cause severe pneumoniae, bacter...

Nicholas S. Briggs, S. Camaione, J. Goodall et al. · Microorganisms · 0 citations

Open access Oct 2026

Clinical Accuracy and Operational Evaluation of a Novel Nanopore Based 16S Diagnostic Pathogen Detection Workflow.

Culture-based methods remain standard practice for pathogenic bacterial detection in routine diagnostic laboratories but frequently fail to identify pathogens, particularly in low bacterial burden or antibiotic-exposed samples. While full-length 16S rRNA sequencing improves detection and taxonomic resolution, its adopt...

Tom Saville, Magdalena Dąbrowska, Pei-Jun Zhang et al. · Journal of Infection · 0 citations