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Open access Oct 2026

Region-specific cellular ecosystems govern divergent remodelling trajectories in hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) exhibits marked regional heterogeneity despite shared sarcomere gene mutations. The molecular basis underlying preferential septal hypertrophy and relative apical preservation remains poorly understood. To define region-specific cellular programs and intercellular signalli...

Y. Tan, Z. Wang, Y. Song et al. · 0 citations

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