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Author

J. García-Verdugo

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Sep 2026

Hypoxic Preconditioning Prevents the Neonatal Lung Against Hyperoxia-Induced Ferroptosis Through the Nrf2-CBS Axis.

AIMS Hyperoxia-induced oxidative injury contributes to ferroptosis and abnormal lung remodeling in preterm infants receiving oxygen therapy. We previously demonstrated that postnatal hypoxic preconditioning (HP) reduces hyperoxia-induced lung injury in a neonatal mouse model. In the present study, we investigated wheth...

Salvador Pérez, Iván Millán, Elena Cubells et al. · 0 citations
Open access Aug 2026

Intracranial Targeting of Cholesterol Processing Reveals a Therapeutic Vulnerability that Reprograms Glioblastoma and Promotes Antitumor Immunity

These findings establish cholesterol dysregulation–induced metabolic collapse as a promising therapeutic approach for GBM using two FDA-approved drugs: the H1 histamine antagonist clemastine and the retinoid X receptor agonist bexarotene.

Maria J. Ulloa-Navas, Rachel M. Whitehead, Vanessa K. Jones et al. · 0 citations

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