Author

J. Gangneux

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Open access Sep 2026

Association of antifungal treatment duration with 90-day mortality in critically ill adults with candidemia: a multicenter target trial emulation in France

Summary Background The optimal duration of antifungal therapy for candidemia in intensive care unit (ICU) patients remains uncertain. We aimed to evaluate whether shorter antifungal therapy was not associated with increased mortality using a target trial emulation framework. Methods We conducted a multicenter cohort st...

F. Reizine, J. Henry, L. Desmedt et al. · EClinicalMedicine · 0 citations

Open access Sep 2026

Early inflammatory macrophage reprogramming by Scedosporium apiospermum determines fungal survival

ABSTRACT Scedosporium is the second most prevalent fungal colonizer of the airways of cystic fibrosis (CF) patients after Aspergillus fumigatus. Chronic bacterial and fungal colonization drives persistent inflammation via damage-associated molecular patterns, contributing to lung injury. Owing to their distinct structu...

H. Guegan, F. Robert-Gangneux, Sarah Dion et al. · Virulence · 0 citations

Open access Sep 2026

First use of rapid ICT screening for Toxoplasma in pregnant women in Ethiopia: A multicenter study in Bahir Dar, Ethiopia

Background Toxoplasma gondii primary infection during pregnancy can lead to congenital transmission and cause serious fetal and neonatal complications. Seroprevalence for toxoplasmosis is an indicator of the intensity of transmission and of the risk of infection during pregnancy, yet such data are limited in Ethiopia....

Y. Gelaw, Gizachew Worku Dagnew, Mulusew Alemneh Sinishaw et al. · PLoS Neglected Tropical Dise... · 0 citations