Single-cell proteomics (SCP) enables direct characterization of cellular states at proteome resolution but remains limited in clinical studies due to challenges in sample collection, storage, and transportation. Here, we systematically evaluated preservation strategies for SCP by comparing fresh, cryopreserved, and par...
Heloísa Monteiro Do Amaral-Prado, J. G. Miyamoto, Daniel José de Figueiredo et al.· Molecular & Cellular Proteom...· 0 citations
The venom of the South American rattlesnake Crotalus durissus terrificus (Cdt) is renowned for its minimalist yet highly toxic arsenal. Intraspecific variability in expressed proteoforms and toxin content has been previously observed in Cdt venom, resulting in heterogeneous biological activities. In light of this, our...
J. G. Miyamoto, Jackelinne Y. Hayashi, G. G. Figueirêdo Leite et al.· Journal of Proteome Research· 0 citations
Snake venom is a complex mixture of molecules and is subject to intraspecific variations due to the influence of abiotic and/or biotic factors, one of which is the animal's ontogeny. Some studies have already shown the influence of age on the composition and properties of snake venom, but these variations are not unifo...
E. O. D. de Lima, Juan David Gutiérrez Marín, L. Tasima et al.· Toxicon· 0 citations
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