Immunological Correlate of Protection by PHV02 Live, Attenuated Recombinant VSV Vaccine Against Nipah Virus Disease Using an Improved Neutralizing Antibody Method, with Considerations for Future Research
Abstract Establishing the immune correlate of protection for a vaccine could be the basis for regulatory approval. The immune correlate of PHV02, a clinical-stage recombinant vesicular stomatitis (rVSV) vaccine against Nipah virus (NiV) disease, was investigated in the African green monkey (AGM) model. Although a mecha...