Author

J. Felix

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Open access Aug 2026

Perinatal risk factors, DNA methylation and the development of ADHD symptoms: a high-dimensional mediation analysis

A role of DNAm at birth in mediating the association of maternal smoking, birth weight and ADHD-related genetic variants with ADHD symptoms is demonstrated, however, lack of individual site-specific findings and the observational design limit causal biological interpretations.

A. Neumann, M. Suderman, J. Felix et al. · medRxiv · 0 citations

Open access Jul 2026

DNA methylation as proxy of genetic, prenatal and perinatal psychiatric risk factors

Background. Cord blood DNA methylation profile scores (MPSs) based on genetic and pre-/perinatal risk factors for neurodevelopmental conditions (NDCs) may capture downstream biological effects and help understand how combined exposure signals contribute to NDC risk. Methods. Using data from two longitudinal birth cohor...

Elena Isaevska, Rosa H. Mulder, I. Schuurmans et al. · medRxiv · 0 citations