Open access
Aug 2026
Assessment of impending pancreatic cancer in a cohort of new onset diabetes on basis of biomarker trajectory
E. Irajizad, C. López, S. Chari et al.
· medRxiv · 0 citations
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Editorial
Open access
Aug 2026
Editorial: Cancer cell metabolism and tumor microenvironment remodel
Graphical Abstract Illustration showing interactions of cancer cells, stromal cells, immune cells, and microbiota in the tumor microenvironment, highlighting specific bioactive metabolites from each cell type and their effects on tumor survival, metabolic support, immune dysfunction, and therapy resistance.
Katsuhiro Yoshimura, Daniela B. Rodriguez-Perera, Rongzhang Dou et al.
· Frontiers in Genetics · 0 citations
Preprint
Sep 2026
Multi-Objective Composite Longitudinal Biomarker Scores for Improved Cancer Risk Assessment
Improved Parametric Empirical Bayes (iPEB), which accounts for the intervals between serial measurements, adjusts for covariates, and performs feature selection and optimized biomarker combination, improved lung cancer risk assessment in independent PLCO data, supporting objective-driven optimization of longitudinal bi...
Bitan Sarkar, Ana M. Kenney, James P. Long et al.
· 0 citations
Open access
Aug 2026
A blood-based signature of cytoskeletal and extracellular remodeling for risk stratification of intraductal papillary mucinous neoplasms
Integrated proteomic and spatial transcriptomic datasets of IPMN tissues revealed coordinated alterations cytoskeletal and ECM remodeling and elevated matrix stiffness as prominent features associated with IPMN/PDAC, which paralleled concordant increases in BGN and ITGB1BP1.
L. Patterson, R. Ballarò, Y. Chen et al.
· medRxiv · 0 citations