Open access
Sep 2026
Mitotic chromosomes are mechanically connected by chromatin-based interchromosome linkers
The spatial organization of chromosomes is crucial for gene regulation and genome stability. Metaphase chromosomes appear physically discrete from one another in conventional chromosome preparations. However, interchromosomal connections, or “linkers”, have been observed among mitotic chromosomes, and may play importan...
Ming-Xuan Sun, Ronald J. Biggs, Omar Akhtar et al.
· bioRxiv · 0 citations