Author

J. Dumfarth

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Open access Sep 2026

Monitoring Mitochondrial Function With High-Resolution Respirometry During Ex-Situ Heart Perfusion.

BACKGROUND Due to the high adenosine-triphosphate (ATP) consumption of the myocardial tissue, cardiac function is dependent on efficient mitochondrial respiration. Ischemia and reperfusion injury (I/R) has a severe impact on the function of the mitochondrial respiratory system. Ex-situ heart perfusion (ESHP) can minimi...

L. Stastny, J. Hofmann, A. T. Meszaros et al. · Artificial Organs · 0 citations

Open access Aug 2026

Insights on Prevalence of Hereditary Aortic Thoracic Disease and Impact on Family Screening in Routine Clinical Cardiothoracic Surgery Care

Objective: Heritable thoracic aortic disease (HTAD) is an important cause of thoracic aortic aneurysm and dissection, yet remains underdiagnosed. We aimed to summarize the prevalence of syndromic and non-syndromic HTAD, describe variants of uncertain significance (VUS), and evaluate the impact of family screening in a...

S. Gasser, M. Graber, N. Bonaros et al. · Genes · 0 citations