Open access
Sep 2026
Spatially distributed growth factor environments for evaluating hydrogel-based CD34+ cell culture conditions
Suspension culture is the gold standard for ex vivo hematopoietic stem cell (HSC) expansion; however, high media requirement results in expensive cell therapy products. Hydrogel-based HSC culture represents a more realistic in vitro representation of human in vivo HSC microenvironments and may support a more efficient...
A. R. Murphy, Rose Ann Franco, P. Johnson et al.
· bioRxiv · 0 citations