Author

J. C. Núñez-Enríquez

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Open access Sep 2026

Exploratory Association of 5′ and 3′ UTRs Variants in TYMS and CCND1 with Severe Hematologic Toxicity in Pediatric Acute Lymphoblastic Leukemia

Mexico has one of the highest incidences of childhood acute lymphoblastic leukemia worldwide and also reports one of the lowest 5-year overall survival rates; one cause is elevated treatment-related mortality from severe hematologic toxicity, a critical side effect during chemotherapy. Although association studies have...

Daniela Rojo-Serrato, Francisco Javier Flores-Murrieta, H. Rosas-Vargas et al. · International Journal of Mol... · 0 citations

Open access Sep 2026

Childhood serum DDE concentrations and acute lymphoblastic leukemia in a high-exposure region of south-central Mexico.

BACKGROUND Childhood acute lymphoblastic leukemia (ALL) is the most common pediatric cancer but its etiology remains largely unknown. Persistent organochlorine pollutants such as p,p'-DDE have been implicated in leukemogenesis, although epidemiological evidence remains scarce and contradictory. We aimed to evaluate the...

Rodrigo Ugalde-Resano, Ángel Mérida-Ortega, Mariano E. Cebrián et al. · Cancer Epidemiology · 0 citations

Review Open access Aug 2026

The Childhood Cancer and Leukemia International Consortium (CLIC): Expanding Global Collaboration in Pediatric Cancer Etiology Research

The integration of genetic ancestry and germline susceptibility data is clarifying ancestry-related differences in leukemia biology and outcomes, while confirming risk loci with population-specific effects.

Ana M. Mora, J. Mejía-Aranguré, J. Dockerty et al. · Cancer Epidemiology · 0 citations