Open access
Mar 2026
Restoring the FOXO1 geroprotective pathway via seno-resistant mesenchymal progenitor cells alleviates primate epididymal aging
Abstract Aging of the male reproductive system is characterized by declining fertility, with epididymal dysfunction being a critical yet poorly understood contributor. Through a multimodal analysis in non-human primates that integrated histology and transcriptomics, we delineated a coherent epididymal aging phenotype e...
Huifen Lu, Lin-Guo Cai, Dongliang Lv et al.
· Protein & Cell · 1 citation