J. C. Gómez

679. From Bench to Clinic: Zatolmilast and the Translation of Neurobiology Research into a Targeted Therapy for Fragile X Syndrome

Abstract Background Drug development in Fragile X syndrome (FXS) has been challenging with multiple development programs failing to achieve positive pivotal study results over decades of continued effort. Meanwhile translational research has continued to lead to the identification of clinically relevant biological path...