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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

J. Bukowski

h-index 6 View on Semantic Scholar

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Jul 2026

Abstract A020: Engineering developability of anti-CD3 scFv-based multispecific T-cell engagers

Stabilized anti-CD3 scFv not only improve properties of two clinical CD20 Fab-based multispecifics but rescue assembly of a third clinical CD20 molecule, which did not produce with the parental, unmodified scFv or with the industry standard engineered disulfide bond VH44-VK100.

Rob Pejchal, Kevin Schutz, Michael B. Battles et al. · 0 citations

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