Open access
Apr 2026
Shared inheritance reveals landscape of somatic and germline cancer risk in TP53
It is demonstrated that somatic rather than germline risk predominates in middle-aged healthy adults and the VAF-haplotype-sharing analysis framework provides a scalable framework for variant classification in large-scale population genomics.
H. A. MacGregor, J. Blundell, D. Easton
· medRxiv · 0 citations