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J. B. Goldberg

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Open access Aug 2026

R-pyocin-mediated selection reverses pan-drug resistance in Pseudomonas aeruginosa

It is demonstrated that R-pyocins can be leveraged not merely as conventional biocides, but as precise selective forces to drive an evolutionary “checkmate” strategy, establishing a framework for using R-pyocins to force predictable evolutionary trade-offs, driving the reversion of multidrug resistance to an attenuated...

Isaac Estrada, Davina Campbell, G. Welch et al. · 0 citations
Open access Jul 2026

LRRK2 G2019S reprograms innate and adaptive immunity to drive context-dependent host defense outcomes

Introduction Parkinson’s disease (PD) is increasingly recognized as a neurological disorder characterized not only by neurodegeneration but also by chronic immune dysregulation across the lifespan. Although the initiating events underlying PD remain unclear, accumulating evidence suggests that inflammatory processes ma...

Andrea R. Merchak, Mary K. Herrick, M. Houser et al. · 0 citations

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