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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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J. A. Martínez

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Open access Sep 2026

Dual control of plasmid copy number in E. coli by combining temperature shifts and RNAI-based genetic circuits for tunable replication dynamics

Plasmid copy number (PCN) is a central determinant of recombinant gene expression levels and metabolic burden in bacterial cell factories. However, dynamic real-time control of PCN during microbial cultivation remains largely unexplored. In the ColE1/pUC19 replication system, PCN is governed by an antisense RNAI/RNAII...

Hannah Sehrt, M. Sehrt, J. A. Martínez et al. · 0 citations

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