Author

Izhar Khan

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Review Open access Aug 2026

Benzothiazole-driven molecular probes and therapeutics for neurodegenerative diseases: focus on amyloid-beta (Aβ), tau, and α-synuclein.

Evidence highlights BZT as one of the most promising privileged scaffolds for integrating early diagnosis, disease monitoring, and disease-modifying intervention within a unified molecular framework for neurodegenerative disorders.

Nitin Kumar, Izhar Khan, Jyoti Singh et al. · RSC Medicinal Chemistry · 1 citation

Review Aug 2026

Recent developments in donepezil-based hybrid molecules as multi-target therapeutics for Alzheimer's disease: A paradigm shift beyond symptomatic treatment.

Rather than presenting DPZ-based hybrids as established disease-modifying therapies, the available evidence supports their role as promising multifunctional lead compounds and valuable molecular platforms for the rational design of next-generation anti-Alzheimer agents.

Nitin Kumar, Izhar Khan, Jyoti Singh et al. · Bioorganic chemistry (Print) · 1 citation