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Author

Ivana Barbaric

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Open access Aug 2026

Integrated sequencing approach to probe rRNA modification landscape during human embryonic stem cell differentiation

By integrating rRNA and snoRNA sequencing approaches, this work has built a comprehensive profile of rRNA modification dynamics during early embryonic cell fate decisions, highlighting potential regulatory mechanisms for ribosome heterogeneity during development.

Tessa W. Y. Chan, Ivana Barbaric, Emma E. Thomson · 0 citations
Open access Jul 2026

HDAC6 inhibition alleviates mitochondrial trafficking in models of Charcot-Marie-Tooth disease type 2A

A variant-specific insight is revealed into CMT2A disease mechanisms and HDAC6 is confirmed as a promising target for further therapeutic development by showing that mitochondrial trafficking defects could be alleviated by treatment with an HDAC6 inhibitor.

Lydia H. Jestice, Larissa Butler, Rebecca A. Lea et al. · 0 citations

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