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Ivan Coelho Machado

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Open access Sep 2026

Is there an interaction between hypertension and proteinuria in pediatric chronic kidney disease progression? Evidence from the SP-CKD-Kids cohort.

BACKGROUND Hypertension and proteinuria are established risk factors for chronic kidney disease (CKD) progression in children. Given their pathophysiological interrelationship, whether their coexistence produces a multiplicative interaction remains uncertain. We evaluated this interaction in a Brazilian pediatric cohor...

Ivan Coelho Machado, M. M. Gabriele, L. Prates et al. · 0 citations

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