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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Israa H. Isawi

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Open access Sep 2026

Structural Prerequisites for Pim-1 Kinase Inhibition and the Identification of a Pyrazolyl-Methylene-Indolinone Hit

Introduction Pim-1 is a serine/threonine kinase of the pan-Pim family (Pim-1, −2, and −3), whose overexpression is associated with various cancers. Its distinctive hinge-region architecture provides opportunities for selective inhibitor development, with several inhibitors reported as clinical candidates. Understanding...

Rufaida Al Zoubi, Omar Hadieh, Soraya Alnabulsi et al. · 0 citations

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