Synthesis, characterization, photophysical properties, and investigation of enzyme inhibition activities of quinazoline based chiral hydrazine-carbothioamides
In this study, two novel chiral quinazoline-thiosemicarbazone compounds (10a and 10b) were synthesized from (L)-valine via a multistep route involving hydroxyl protection, chlorination, hydrazination, isothiocyanate addition, and TBDMS deprotection. Structures were confirmed by ¹H-NMR, ¹³C-NMR, and IR spectroscopy. Pho...