Author

İsmail Bolat

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Jul 2026

Protective Effects of p-Coumaric Acid Against Lead-Induced Hepatic Oxidative Stress, Inflammation, and Apoptosis: Integrated Molecular and Machine Learning-Based Analysis.

Overall, PCA alleviates Pb-induced hepatotoxicity by restoring antioxidant defenses, suppressing inflammatory signalling, and inhibiting mitochondrial apoptotic pathways.

I. Bozkurt, Yeliz Demir, Tuba Karaarslan et al. · Environmental Toxicology and... · 1 citation

Aug 2026

Morin attenuates vancomycin-induced nephrotoxicity via Nrf-2/HO-1, SIRT1/PGC1α and AKT/FOXO1A pathways

Morin (MOR) treatment significantly ameliorated VCM-induced renal injury by reducing oxidative injury, restoring endogenous defense systems, attenuating inflammatory responses, suppressing apoptosis, and markedly improving histopathological lesions.

S. Tekin, Merve Bolat, Burak Batuhan Laçin et al. · Molecular Biology Reports · 0 citations

Aug 2026

p-Coumaric Acid Attenuates Lead Acetate-induced Neurotoxicity in Rats by Improving Behavioral Dysfunction and Suppressing Oxidative Stress, Neuroinflammation, Apoptosis, and Plasticity-related Molecular Alterations.

It is suggested that p-coumaric acid exerts neuroprotective effects against PbAc-induced brain injury by attenuating oxidative stress, neuroinflammation, and apoptosis while supporting neuronal plasticity.

Tuba Karaarslan, Merve Bolat, İsmail Bolat et al. · Biological Trace Element Res... · 0 citations