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Isaiah Rozich

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Open access Jul 2026

Notch2 signaling instructs viral and bacterial TLR responsiveness in B cells.

It is revealed that constitutive Notch2 experience affords lipopolysaccharide (LPS) hyperresponsiveness in Notch2-independent follicular B cells, which resulted in earlier Myc induction and accelerated cell cycle entry, ultimately augmenting division kinetics.

Jennifer Londregan, Isaiah Rozich, Brian T. Gaudette et al. · 0 citations

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