Isabella Giambó-Falian

From phenotype to gene during the oocyte-to-embryo transition: Integrating genetic and sequencing-based strategies to identify maternal-effect genes in zebrafish.

Identifying the genetic basis of phenotypes arising during early development remains a central challenge in biology. The oocyte-to-embryo transition (OET) and early embryogenesis are uniquely dependent on maternally supplied factors and tightly regulated post-transcriptional programs, making the identification of mater...